Clinical Evaluation Of Anti – Hyperglycemic Activity Of Phyllanthus Amarus Linn. With Special Reference To Diabetes Mellitus
Diabetes mellitus is the one of the five most attention needy diseases throughout the world. This disease is presently a burden not only on the individuals affected by the disease but also on society. Bhumyamalakibeingtikta, kashayain rasa, is act as medohara in the manifestation of the disease. So this drug is being used in madhumehaas folklore medicine.Open labeled randomized study was done in Seth R.V.Mahavidyalaya,Sion; Mumbai-022.
The study comprises total 60 patients. Group A include 30 patients which were given 3gms of Bhumiamyamalki churnatwice orally with ushnodak as anupan and group B was control group of 30 patients were given yavachurna. Subjective criteria was assessed based on following symptoms-Daurbalya (Weakness both generalized and of a particular part),Ksheenakameccha (Diminished libido), Hastapadataldaha(Burning sensation),Shula (Pain), Pindikodwesta(Cramps), Kshudavruddhi (Excessive Hunger). Objective improvement was done on the basis ofFasting& post prandial blood sugar levels at start and end of study in diabeticpatients.Subjective improvement is shown in percentage. Unpaired t test was applied to objective parameters which was highly significant at 1% level of significance i.e. p<0.01.in patients taking Bhumyamalkichurnawhile in other group it was significant at 5% level of significance,concluding definitely Bhumyamalkichurna has anti-hyperglycemic activity.There was significant improvement in hastapadtaldaha, pindikodweta, kshudavruddi symptoms.
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